The University of Chicago Header Logo

Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
Refetoff, Samuel
One or more keywords matched the following items that are connected to Refetoff, Samuel
Item TypeName
Concept Dependovirus
Concept Adenoviridae
Concept Aged, 80 and over
Concept Haplorhini
Concept Adolescent
Concept Aged
Concept Amino Acids
Concept Bile Acids and Salts
Concept Amino Acid Sequence
Concept Adult
Concept Central Nervous System Diseases
Concept Animals
Concept Animals, Newborn
Concept Anura
Concept Coliphages
Concept B-Lymphocytes
Concept Base Sequence
Concept Biological Transport, Active
Concept Aspartic Acid
Concept Biological Transport
Concept Cattle
Concept Child
Concept Complement System Proteins
Concept Cell-Free System
Concept Genetic Vectors
Concept Guinea Pigs
Concept Cricetulus
Concept Computers
Concept Hearing Loss, Sensorineural
Concept Homozygote
Concept Defective Viruses
Concept Endocrine System Diseases
Concept Child, Preschool
Concept Dogs
Concept Jews
Concept Litter Size
Concept Hypothalamo-Hypophyseal System
Concept Chronic Disease
Concept Family
Concept Fatty Liver
Concept Infant, Newborn
Concept Infant, Premature
Concept Mice, Inbred C3H
Concept Fatty Acids
Concept Fatty Acids, Unsaturated
Concept Terminology as Topic
Concept Half-Life
Concept Nucleic Acid Hybridization
Concept Dwarfism, Pituitary
Concept beta-Lipotropin
Concept Liver Neoplasms
Concept Long-Acting Thyroid Stimulator
Concept Enzyme-Linked Immunosorbent Assay
Concept Herpesvirus 4, Human
Concept Escherichia coli
Concept Feedback
Concept Infant
Concept Goats
Concept Lactation Disorders
Concept Leucine
Concept Light
Concept Lung Diseases
Concept Labor, Obstetric
Concept Leukocytes
Concept Leydig Cells
Concept Mice, Inbred Strains
Concept Mice, Transgenic
Concept Molecular Sequence Data
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Middle Aged
Concept Cricetinae
Concept RNA, Transfer, Amino Acyl
Concept Isotope Labeling
Concept Nervous System Diseases
Concept Laminin
Concept Leg Dermatoses
Concept Nucleic Acid Conformation
Concept Ligands
Concept Liver
Concept Luciferases
Concept Lung Neoplasms
Concept Nuclear Family
Concept Placental Lactogen
Concept Rabbits
Concept Rats, Zucker
Concept Receptors, LH
Concept Sequence Homology, Nucleic Acid
Concept Receptors, LDL
Concept Xenopus
Concept Iopanoic Acid
Concept Islam
Concept Shrews
Concept Rats, Inbred Lew
Concept Regulatory Sequences, Nucleic Acid
Concept Polymorphism, Restriction Fragment Length
Concept Swine
Concept Sheep
Concept Sympathetic Nervous System
Concept Humans
Concept Twins, Monozygotic
Concept Twins
Concept Sequence Homology, Amino Acid
Concept Xenopus laevis
Concept Islets of Langerhans
Concept Germ-Line Mutation
Concept Lung
Concept Liver Glycogen
Concept Lysosomes
Concept Weight Loss
Concept Trichloroacetic Acid
Concept Models, Animal
Concept LDL-Receptor Related Protein-Associated Protein
Concept Mice, Inbred DBA
Concept Mice, Inbred ICR
Concept Genomic Library
Concept Rats, Sprague-Dawley
Concept Rats, Wistar
Concept Mice, Obese
Concept Mitochondria, Liver
Concept Receptors, Retinoic Acid
Concept Mice, Knockout
Concept Basic-Leucine Zipper Transcription Factors
Concept Jet Lag Syndrome
Concept Rats, Inbred Dahl
Concept Protein Transport
Concept Amino Acid Transport Systems, Neutral
Concept Fusion Regulatory Protein 1, Light Chains
Concept Arabs
Concept Nucleic Acid Denaturation
Concept Genetic Diseases, X-Linked
Concept Mental Retardation, X-Linked
Concept Clinical Laboratory Techniques
Concept Amino Acid Substitution
Concept Leptin
Concept Active Transport, Cell Nucleus
Concept Databases, Genetic
Concept Monocarboxylic Acid Transporters
Concept Organic Cation Transport Proteins
Concept Organic Anion Transporters, Sodium-Independent
Concept Animals, Genetically Modified
Concept Mice
Concept Rats, Inbred BN
Concept Rats, Inbred Strains
Concept Saccharomyces cerevisiae
Concept Research Design
Concept Acute Lung Injury
Concept Lingual Goiter
Concept Rats
Concept Sialic Acids
Concept Zebrafish
Concept Mice, 129 Strain
Concept Butyric Acid
Concept Repetitive Sequences, Amino Acid
Concept Low Density Lipoprotein Receptor-Related Protein-2
Concept Anion Transport Proteins
Concept Leukocyte Elastase
Concept Chemical and Drug Induced Liver Injury
Concept Two-Hybrid System Techniques
Concept MAP Kinase Signaling System
Concept Organic Anion Transporters
Concept Ventilator-Induced Lung Injury
Concept Siblings
Concept Cell Line, Tumor
Concept Lipid Metabolism
Concept Cell Line
Concept Heterozygote
Concept Horses
Concept Luteinizing Hormone
Concept Genetic Linkage
Concept Longitudinal Studies
Concept Luminescent Proteins
Concept Lymphocyte Activation
Concept Lymphocytes
Concept Lysine
Concept Mice, Mutant Strains
Concept Mothers
Concept Phylogeny
Concept Pituitary-Adrenal System
Concept Membrane Transport Proteins
Concept Amino Acid Transport System y+
Concept Amino Acid Transport System y+L
Concept Lipogenesis
Concept Glucose Transporter Type 4
Concept Young Adult
Academic Article The relative expression of mutant and normal thyroid hormone receptor genes in patients with generalized resistance to thyroid hormone determined by estimation of their specific messenger ribonucleic acid products.
Academic Article In vitro expression of thyroxine-binding globulin (TBG) variants. Impaired secretion of TBGPRO-227 but not TBGPRO-113.
Academic Article Expression of thyroid peroxidase in EBV-transformed B cell lines using adenovirus.
Academic Article A mouse model of resistance to thyroid hormone produced by somatic gene transfer of a mutant thyroid hormone receptor.
Academic Article Thyroid dysfunction is not associated with alterations in serum leptin levels.
Academic Article Resistance to thyrotropin and other abnormalities of the thyrotropin receptor.
Academic Article Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH.
Academic Article Two different mutations in the thyroid peroxidase gene of a large inbred Amish kindred: power and limits of homozygosity mapping.
Academic Article Iodination-deiodination. A radiochemical method for detection of structure and changes in structure in RNA.
Academic Article An additional carbohydrate chain in the variant thyroxine-binding globulin-Gary (TBGAsn-96) impairs its secretion.
Academic Article Selective pituitary resistance to thyroid hormone produced by expression of a mutant thyroid hormone receptor beta gene in the pituitary gland of transgenic mice.
Academic Article Structure-function relationships of two loss-of-function mutations of the thyrotropin receptor gene.
Academic Article Modification of thyroid hormone and 9-cis retinoic acid signaling by overexpression of their cognate receptors using adenoviral vector.
Academic Article Effect of thyroid hormone on growth. Lessons from the syndrome of resistance to thyroid hormone.
Academic Article Dominant inheritance of resistance to thyroid hormone not linked to defects in the thyroid hormone receptor alpha or beta genes may be due to a defective cofactor.
Academic Article Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice.
Academic Article Familial dysalbuminemic hyperthyroxinemia in a Swiss family caused by a mutant albumin (R218P) shows an apparent discrepancy between serum concentration and affinity for thyroxine.
Academic Article Congenital central isolated hypothyroidism caused by a homozygous mutation in the TSH-beta subunit gene.
Academic Article Sequencing of the variant thyroxine-binding globulin (TBG)-San Diego reveals two nucleotide substitutions.
Academic Article Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism.
Academic Article Identification of thyroxine-binding globulin-San Diego in a family from Houston and its characterization by in vitro expression using Xenopus oocytes.
Academic Article Low serum free thyroxine index in ambulating elderly is due to a resetting of the threshold of thyrotropin feedback suppression.
Academic Article Responsiveness to thyroid hormone is enhanced in rat hepatocytes cultured as spheroids compared with that in monolayers: altered responsiveness to thyroid hormone possibly involves complex formed on thyroid hormone response elements.
Academic Article Five new families with resistance to thyroid hormone not caused by mutations in the thyroid hormone receptor beta gene.
Academic Article Torpor in mice is induced by both leptin-dependent and -independent mechanisms.
Academic Article Complete thyroxine-binding globulin (TBG) deficiency produced by a mutation in acceptor splice site causing frameshift and early termination of translation (TBG-Kankakee).
Academic Article Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance.
Academic Article Rapid localization of mutations in the thyroid hormone receptor-beta gene by denaturing gradient gel electrophoresis in 18 families with thyroid hormone resistance.
Academic Article Improved radioimmunoassay for measurement of mouse thyrotropin in serum: strain differences in thyrotropin concentration and thyrotroph sensitivity to thyroid hormone.
Academic Article Recessive inheritance of thyroid hormone resistance caused by complete deletion of the protein-coding region of the thyroid hormone receptor-beta gene.
Academic Article Complete thyroxine-binding globulin (TBG) deficiency in two families without mutations in coding or promoter regions of the TBG genes: in vitro demonstration of exon skipping.
Academic Article Characterization of T(4)-binding globulin cleaved by human leukocyte elastase.
Academic Article Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo.
Academic Article Type 1 iodothyronine deiodinase in the house musk shrew (Suncus murinus, Insectivora: Soricidae): cloning and characterization of complementary DNA, unique tissue distribution and regulation by T(3).
Academic Article Search for abnormalities of nuclear corepressors, coactivators, and a coregulator in families with resistance to thyroid hormone without mutations in thyroid hormone receptor beta or alpha genes.
Academic Article Low TSH requirement and goiter in transgenic mice overexpressing IGF-I and IGF-Ir receptor in the thyroid gland.
Academic Article RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor.
Academic Article The effect of short-term treatment with recombinant human thyroid-stimulating hormones on leydig cell function in men.
Academic Article Reduced nuclear triiodothyronine receptors in starvation-induced hypothyroidism.
Academic Article Resistance to thyrotropin.
Academic Article A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene.
Academic Article Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.
Academic Article Sequence of the variant thyroxine-binding globulin (TBG) in a Montreal family with partial TBG deficiency.
Academic Article Pseudomalabsorption of levothyroxine.
Academic Article Regression of a large goiter in a patient with resistance to thyroid hormone by every other day treatment with triiodothyronine.
Academic Article Genomic organization of mouse ZAKI-4 gene that encodes ZAKI-4 alpha and beta isoforms, endogenous calcineurin inhibitors, and changes in the expression of these isoforms by thyroid hormone in adult mouse brain and heart.
Academic Article Partial deficiency of thyroxine-binding globulin-Allentown is due to a mutation in the signal peptide.
Academic Article Three novel mutations causing complete T(4)-binding globulin deficiency.
Academic Article Characterization and primary structures of bovine and porcine thyroxine-binding globulin.
Academic Article Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice.
Academic Article Fetal loss associated with excess thyroid hormone exposure.
Academic Article A de novo mutation in an already mutant nucleotide of the thyroid hormone receptor beta gene perpetuates resistance to thyroid hormone.
Academic Article Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo.
Academic Article Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci.
Academic Article Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.
Academic Article Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1.
Academic Article Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface.
Academic Article Nuclear receptors for thyroid hormone.
Academic Article Unique regulation of thyroid hormone metabolism during fasting in the house musk shrew (Suncus murinus, Insectivora: Soricidae).
Academic Article Sequencing of the variant thyroxine-binding globulin (TBG)-Quebec reveals two nucleotide substitutions.
Academic Article Preferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: a control mechanism for thyroid hormone release.
Academic Article Replacement of Leu227 by Pro in thyroxine-binding globulin (TBG) is associated with complete TBG deficiency in three of eight families with this inherited defect.
Academic Article Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice.
Academic Article Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
Academic Article Molecular basis for the properties of the thyroxine-binding globulin-slow variant in American blacks.
Academic Article Abnormalities of triiodothyronine binding to lymphocyte and fibroblast nuclei from a patient with peripheral tissue resistance to thyroid hormone action.
Academic Article The syndrome of resistance to thyroid stimulating hormone.
Academic Article Clinical and genetic characteristics of congenital hypothyroidism due to mutations in the thyroid peroxidase (TPO) gene in Israelis.
Academic Article International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors.
Academic Article Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells.
Academic Article Effects of maternal levels of thyroid hormone (TH) on the hypothalamus-pituitary-thyroid set point: studies in TH receptor beta knockout mice.
Academic Article Syndromes of reduced sensitivity to thyroid hormone: genetic defects in hormone receptors, cell transporters and deiodination.
Academic Article Familial juvenile autoimmune hypothyroidism, pituitary enlargement, obesity, and insulin resistance.
Academic Article Sleep deprivation in the rat: XI. The effect of guanethidine-induced sympathetic blockade on the sleep deprivation syndrome.
Academic Article Effect of total sleep deprivation on 5'-deiodinase activity of rat brown adipose tissue.
Academic Article Comparison of primary and secondary stimulation of male rats by estradiol in terms of prolactin synthesis and mRNA accumulation in the pituitary.
Academic Article Multiple endocrine neoplasia 2A syndrome presenting as peripartum cardiomyopathy due to catecholamine excess.
Academic Article Loss-of-function mutations in the thyrotropin receptor gene as a major determinant of hyperthyrotropinemia in a consanguineous community.
Academic Article Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine.
Academic Article X-linked paroxysmal dyskinesia and severe global retardation caused by defective MCT8 gene.
Academic Article Tissue responses to thyroid hormone in a kindred with resistance to thyroid hormone harboring a commonly occurring mutation in the thyroid hormone receptor beta gene (P453T).
Academic Article The syndrome of inherited partial SBP2 deficiency in humans.
Academic Article Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent.
Academic Article A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport.
Academic Article Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta.
Academic Article Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.
Academic Article Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.
Academic Article Pendred syndrome in two Galician families: insights into clinical phenotypes through cellular, genetic, and molecular studies.
Academic Article Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo.
Academic Article Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis.
Academic Article A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
Academic Article Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors.
Academic Article A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 mutation and monoallelic DUOXA1 deletion.
Academic Article Homozygous thyroid hormone receptor ß-gene mutations in resistance to thyroid hormone: three new cases and review of the literature.
Academic Article Inherited thyroxine-binding globulin abnormalities in man.
Academic Article Transsphenoidal surgery for Cushing disease: experience with 136 patients.
Academic Article Role of type 2 deiodinase in response to acute lung injury (ALI) in mice.
Academic Article Effect of estrogen on the synthesis and secretion of thyroxine-binding globulin by a human hepatoma cell line, Hep G2.
Academic Article Normal cellular uptake of thyroxine from serum of patients with familial dysalbuminemic hyperthyroxinemia or elevated thyroxine-binding globulin.
Academic Article Characterization of thyroxine-binding globulin secreted by a human hepatoma cell line.
Academic Article Isoelectric focusing variant thyroxine-binding globulin in American blacks: increased heat lability and reduced serum concentration.
Academic Article X-chromosome-linked inheritance of the variant thyroxine-binding globulin in Australian aborigines.
Academic Article High concentration of thyrotropin-releasing hormone in pancreatic islets.
Academic Article Hybridization of RNA labelled with 125 I to high specific activity.
Academic Article The effects of low doses of depot estradiol and testosterone in teenagers with ovarian failure and Turner's syndrome.
Academic Article Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone.
Academic Article Elevated serum thyroglobulin level in congenital thyroxine-binding globulin deficiency.
Academic Article Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes.
Academic Article Resistance to thyroid hormone in a patient with thyroid dysgenesis.
Academic Article Effects of "jet lag" on hormonal patterns. III. Demonstration of an intrinsic circadian rhythmicity in plasma prolactin.
Academic Article Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation.
Academic Article The syndromes of resistance to thyroid hormone.
Academic Article Identification of a functional polymorphism of the human type 5 17beta-hydroxysteroid dehydrogenase gene associated with polycystic ovary syndrome.
Academic Article Sequence of the variant thyroxine-binding globulin of Australian aborigines. Only one of two amino acid replacements is responsible for its altered properties.
Academic Article Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
Academic Article A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone.
Academic Article T3 thyrotoxicosis. Thyrotoxicosis due to elevated serum triiodothyronine levels.
Academic Article The differential stimulatory effect of thyroid hormone on growth hormone synthesis and estrogen on prolactin synthesis due to accumulation of specific messenger ribonucleic acids.
Academic Article Suppression of serum thyrotropin (TSH) by L-dopa in chronic hypothyroidism: interrelationships in the regulation of TSH and prolactin secretion.
Academic Article Inherited X chromosome linked thyroxine-binding globulin (TBG) deficiency in a homozygous female.
Academic Article Multiple complications of propylthiouracil treatment: granulocytopenia, eosinophilia, skin reaction and hepatitis with lymphocyte sensitization.
Academic Article Mosaicism of a thyroid hormone receptor-beta gene mutation in resistance to thyroid hormone.
Academic Article Ontogenetic patterns of thyrotropin-releasing hormone-like material in rat hypothalamus, pancreas, and retina: selective effect of light deprivation.
Academic Article The role of glycosylation in the molecular conformation and secretion of thyroxine-binding globulin.
Academic Article Radioautographic localization of prolactin messenger RNA on histological sections by in situ hybridization.
Academic Article Molecular and structural characterization of the heat-resistant thyroxine-binding globulin-Chicago.
Academic Article Nuclear triiodothyronine-binding protein: partial characterization and binding to chromatin.
Academic Article The preparation of carrier-free iodine isotope-substituted cytosine nucleotides.
Academic Article Alterations in thyroxine (T 4 ) and tri-iodothyronine (T 3 ) binding to serum proteins by heat.
Academic Article Direct application of radioiodinated aminoacyl tRNA for radiolabeling nascent proteins.
Academic Article Measurement of thyroxine uptake from serum by cultured human hepatocytes as an index of thyroid status: reduced thyroxine uptake from serum of patients with nonthyroidal illness.
Academic Article Resistance to thyroid hormone diagnosed by the reduced response of fibroblasts to the triiodothyronine-induced suppression of fibronectin synthesis.
Academic Article Genetic polymorphism in rhesus C3 and Gc globulin.
Academic Article Immunoreactive growth hormone in endemic cretins in Ecuador.
Academic Article Chiari-Frommel syndrome in a patient with primary adrenocortical insufficiency.
Academic Article Estimation of the T 4 binding capacity of serum TBG and TBPA by a single T 4 load ion exchange resin method.
Academic Article Effects of "jet lag" on hormonal patterns. I. Procedures, variations in total plasma proteins, and disruption of adrenocorticotropin-cortisol periodicity.
Academic Article Peroxidase defect in congenital goiter with complete organification block.
Academic Article TBG deficiency: description of two novel mutations associated with complete TBG deficiency and review of the literature.
Academic Article Loss of bioreactivity and preservation of immunoreactivity of iodothyrotropin-releasing hormone.
Academic Article Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism.
Academic Article Bidirectional thyroxine exchange in pregnant sheep.
Academic Article Hyperthyroidism and adult celiac disease.
Academic Article Metabolism of L-thyroxine (T4) and L-triiodothyronine (T3) by human fibroblasts in tissue culture: evidence for cellular binding proteins and conversion of T4 to T3.
Academic Article Regulation of glycosaminoglycan synthesis by thyroid hormone in vitro.
Academic Article Effects of "jet lag" on hormonal patterns. II. Adaptation of melatonin circadian periodicity.
Academic Article Modulation of thyroglobulin messenger RNA accumulation in the rat thyroid.
Academic Article Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor.
Academic Article Isolation of rat prolactin messenger ribonucleic acid and synthesis of the complementary deoxyribonucleic acid.
Academic Article Low intelligence but not attention deficit hyperactivity disorder is associated with resistance to thyroid hormone caused by mutation R316H in the thyroid hormone receptor beta gene.
Academic Article Mutations of CpG dinucleotides located in the triiodothyronine (T3)-binding domain of the thyroid hormone receptor (TR) beta gene that appears to be devoid of natural mutations may not be detected because they are unlikely to produce the clinical phenotype of resistance to thyroid hormone.
Academic Article Preliminary studies on the immediate phase-shifting effects of light and exercise on the human circadian clock.
Academic Article Diurnal rhythm in total serum thyroxine levels.
Academic Article Pituitary-thyroid setpoint and thyrotropin receptor expression in consomic rats.
Academic Article Brief report: resistance to thyrotropin caused by mutations in the thyrotropin-receptor gene.
Academic Article Radioiodine labeling of ribopolymers for special applications in biology.
Academic Article Sleep deprivation in the rat: XIX. Effects of thyroxine administration.
Academic Article Pretibial myxedema--a reversible cause of foot drop due to entrapment of the peroneal nerve.
Academic Article Interrelationships in the regulation of TSH and prolactin secretion in man: effects of L-dopa, TRH and thyroid hormone in various combinations.
Academic Article Congenital neonatal hyperthyroidism caused by germline mutations in the TSH receptor gene.
Academic Article Familial goitre with partial iodine organification defect, lack of thyroglobulin, and high levels of thyroid peroxidase.
Academic Article Radioimmunoassays specific for the tertiary and primary structures of thyroxine-binding globulin (TBG): measurement of denatured TBG in serum.
Academic Article Simultaneous translation of growth hormone and prolactin messenger RNA from rat pituitary tumor cells.
Academic Article Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred.
Academic Article Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers.
Academic Article White matter abnormalities and dystonic motor disorder associated with mutations in the SLC16A2 gene.
Academic Article Functional characteristics of a variant thyrotropin receptor.
Academic Article Distinct roles of deiodinases on the phenotype of Mct8 defect: a comparison of eight different mouse genotypes.
Academic Article Multifactorial control of the 24-hour secretory profiles of pituitary hormones.
Academic Article Nuclear thyroid hormone receptors in cultured human fibroblasts: improved method of isolation, partial characterization, and interaction with chromatin.
Academic Article Inherited abnormality of thyroxine-binding globulin with no demonstrable thyroxine-binding activity and high serum levels of denatured thyroxine-binding globulin.
Academic Article A rapid radioimmunoassay for human placental lactogen. Application to normal and pathologic pregnancies.
Academic Article The radioiodination of ribopolymers for use in hybridizational and molecular analyses.
Academic Article Effects of "jet lag" on hormonal patterns. IV. Time shifts increase growth hormone release.
Academic Article Response to challenge with gonadotropin-releasing hormone agonist in a mother and her two sons with a constitutively activating mutation of the luteinizing hormone receptor--a clinical research center study.
Academic Article Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.
Academic Article Behavioral effects of liothyronine (L-T3) in children with attention deficit hyperactivity disorder in the presence and absence of resistance to thyroid hormone.
Academic Article Hypothyroidism in a Brazilian kindred due to iodide trapping defect caused by a homozygous mutation in the sodium/iodide symporter gene.
Academic Article Mutation in the thyroid hormone receptor beta gene (A317T) in a Thai subject with resistance to thyroid hormone.
Academic Article Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site.
Academic Article A novel point mutation in cluster 3 of the thyroid hormone receptor beta gene (P247L) causing mild resistance to thyroid hormone.
Academic Article Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha.
Academic Article Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
Academic Article Molecular cloning and primary structure of rat thyroxine-binding globulin.
Academic Article Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
Academic Article Resistance to thyroid hormone.
Academic Article Repulsive separation of the cytoplasmic ends of transmembrane helices 3 and 6 is linked to receptor activation in a novel thyrotropin receptor mutant (M626I).
Academic Article Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.
Academic Article Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism.
Academic Article A novel monocarboxylate transporter 8 gene mutation as a cause of severe neonatal hypotonia and developmental delay.
Academic Article Thyroid hormone receptor beta gene mutation (P453A) in a family producing resistance to thyroid hormone.
Academic Article The action of thyroid hormone.
Academic Article Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.
Academic Article Genetic causes of congenital hypothyroidism due to dyshormonogenesis.
Academic Article Leukocyte alkaline phosphatase in hypothyroidism and hyperthyroidism. Response to initiation of thyroxine replacement therapy.
Academic Article Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation.
Academic Article Detection of the thyroxine-binding globulin (TBG) gene in six unrelated families with complete TBG deficiency.
Academic Article Reduced affinity for thyroxine in two of three structural thyroxine-binding prealbumin variants associated with familial amyloidotic polyneuropathy.
Academic Article Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: a mechanism for estrogen-induced elevation of serum TBG concentration.
Academic Article Study of four new kindreds with inherited thyroxine-binding globulin abnormalities. Possible mutations of a single gene locus.
Academic Article Neonatal hypothyroidism and goiter in one infant of each of two sets of twins due to maternal therapy with antithyroid drugs.
Academic Article Radioimmunoassay of anterior pituitary hormones.
Academic Article Studies on human thyroxine-binding globulin (TBG). IX. Some physical, chemical, and biological properties of radioiodinated TBG and partially desialylated TBG.
Academic Article Radioimmunoassay detection of endorphins from long-term culture of human pituitary tumour cells.
Academic Article Reduced triiodothyronine content in liver but not pituitary of the uremic rat model: demonstration of changes compatible with thyroid hormone deficiency in liver only.
Academic Article Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency.
Academic Article The syndromes of reduced sensitivity to thyroid hormone.
Academic Article A clinically euthyroid child with a large goiter due to a thyroglobulin gene defect: clinical features and genetic studies.
Academic Article Management of differentiated thyroid cancer in the presence of resistance to thyroid hormone and TSH-secreting adenomas: a report of four cases and review of the literature.
Academic Article Changes in thyroid status during perinatal development of MCT8-deficient male mice.
Academic Article A novel mechanism of inherited TBG deficiency: mutation in a liver-specific enhancer.
Academic Article Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.
Academic Article Familial dysalbuminemic hyperthyroxinemia in a 4-year-old girl with hyperactivity, palpitations and advanced dental age: how gold standard assays may be misleading.
Academic Article Mutations of the thyroid hormone transporter MCT8 cause prenatal brain damage and persistent hypomyelination.
Academic Article Long-term outcome of loss-of-function mutations in thyrotropin receptor gene.
Academic Article Inherited defects of thyroid hormone-cell-membrane transport: review of recent findings.
Academic Article Mct8-deficient mice have increased energy expenditure and reduced fat mass that is abrogated by normalization of serum T3 levels.
Academic Article Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8).
Academic Article A new family with an activating mutation (G431S) in the TSH receptor gene: a phenotype discussion and review of the literature.
Academic Article A novel mutation in the Albumin gene (R218S) causing familial dysalbuminemic hyperthyroxinemia in a family of Bangladeshi extraction.
Academic Article Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.
Academic Article Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.
Academic Article Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.
Academic Article Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression.
Academic Article A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.
Academic Article The Thyroid Hormone Analog DITPA Ameliorates Metabolic Parameters of Male Mice With Mct8 Deficiency.
Academic Article Diiodothyropropionic acid (DITPA) cross-reacts with thyroid function assays on different immunoassay platforms.
Academic Article Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model.
Academic Article Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice.
Academic Article Aberrant Cerebellar Development in Mice Lacking Dual Oxidase Maturation Factors.
Academic Article Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.
Academic Article Adeno Associated Virus 9-Based Gene Therapy Delivers a Functional Monocarboxylate Transporter 8, Improving Thyroid Hormone Availability to the Brain of Mct8-Deficient Mice.
Academic Article Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.
Academic Article A Novel Mutation (S54C) of the PAX8 Gene in a Family with Congenital Hypothyroidism and a High Proportion of Affected Individuals.
Academic Article Thyroid Hormone Action on Liver, Heart, and Energy Expenditure in Thyroid Hormone Receptor ß-Deficient Mice* * Presented in part at the 69th Annual Meeting of the American Thyroid Association Meeting, November 14-17, 1996, San Diego, California. This study was supported in part by the National Institutes of Health Grant DK-17050 and the Seymour J. Abrams Thyroid Research Center; a grant from the Ministry of Health and Welfare, Japan (to H.S.); and Grant-in-Aid for Scientific Research (0967104...
Academic Article Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier.
Academic Article Changes in Hepatic TRß Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.
Academic Article Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice.
Academic Article An Essential Physiological Role for MCT8 in Bone in Male Mice.
Academic Article Novel Mutations in the NKX2.1 gene and the PAX8 gene in a Boy with Brain-Lung-Thyroid Syndrome.
Academic Article Homozygous Mutation in Human Serum Albumin and Its Implication on Thyroid Tests.
Academic Article Prenatal Diagnosis of Resistance to Thyroid Hormone and Its Clinical Implications.
Academic Article Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism.
Academic Article Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.
Academic Article GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.
Academic Article NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.
Academic Article Reduced Sensitivity to Thyroid Hormone as a Transgenerational Epigenetic Marker Transmitted Along the Human Male Line.
Academic Article A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia.
Academic Article Interconnection between circadian clocks and thyroid function.
Academic Article Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice.
Academic Article Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis.
Academic Article Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8.
Academic Article Free Thyroxine Concentrations in Sera of Individuals with Familial Dysalbuminemic Hyperthyroxinemia: A Comparison of Three Methods of Measurement.
Academic Article Sorting Variants of Unknown Significance Identified by Whole Exome Sequencing: Genetic and Laboratory Investigations of Two Novel MCT8 Variants.
Academic Article Central Congenital Hypothyroidism Caused by a Novel Mutation, C47W, in the Cysteine Knot Region of TSHß.
Academic Article Intranasal delivery of Thyroid hormones in MCT8 deficiency.
Academic Article Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels.
Academic Article Prenatal Treatment of Thyroid Hormone Cell Membrane Transport Defect Caused by MCT8 Gene Mutation.
Academic Article SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies.
Academic Article Increased Hepatic Fat Content in Patients with Resistance to Thyroid Hormone Beta.
Academic Article Resistance to Thyroid Hormone Beta: A Focused Review.
Academic Article Measurement of Reverse Triiodothyronine Level and the Triiodothyronine to Reverse Triiodothyronine Ratio in Dried Blood Spot Samples at Birth May Facilitate Early Detection of Monocarboxylate Transporter 8 Deficiency.
Academic Article Triiodothyroacetic Acid Cross-Reacts With Measurement of Triiodothyronine (T3) on Various Immunoassay Platforms.
Academic Article XB130 Plays an Essential Role in Folliculogenesis Through Mediating Interactions Between Microfilament and Microtubule Systems in Thyrocytes.
Academic Article TSHB R75G is a founder variant and prevalent cause of low or undetectable TSH in Indian Jews.
Academic Article AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency.
Academic Article A Novel Pathogenic Variant in PAX8 Leads to Familial Congenital Hypothyroidism.
Concept Acid Sensing Ion Channels
Concept Myeloid Cell Leukemia Sequence 1 Protein
Grant 3RD INTERNATL WORKSHOP ON RESISTANCE TO THYROID HORMONE
Grant THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERS
Grant Thyroid Physiology Studies of Inherited Disorders
Grant STUDIES ON REGULATION AND MECHANISM OF HORMONE ACTION
Academic Article Increased cardiovascular morbidity and mortality in patients with resistance to thyroid hormone.
Academic Article ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice.
Academic Article Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome.
Search Criteria
  • Amino
  • Acid
  • Transport
  • System
  • y
  • L